Versions of the scale for use in clinical trials
The Baseline version of the scale assesses lifetime suicidal ideation and behavior. This version is suitable as part of a patient’s first interview in a private practice or as part of a clinical study.
The Already Enrolled Subjects version assesses suicidality since the subject has begun taking part in a clinical trial and over their lifetime. This version is suitable to assess suicidality in subjects who have already been enrolled in a clinical trial but have not yet been assessed using the C-SSRS as part of the trial. This is useful for determining any effects that a particular treatment method may have had on suicidality.
The Since Last Visit version of the scale assesses suicidality since the patient’s last visit. This version is meant to assess patients who have completed at least one initial C-SSRS assessment, and should be used in every subsequent visit. The ‘Since Last Visit’ version of the C-SSRS is asking about any suicidal thoughts or behaviors the patient/participant may have had since the last time you have administered the C-SSRS.
The Screening version of the scale assesses suicidality during a predefined time period. This version is meant to assess patient eligibility based on study-defined suicidality inclusion/exclusion criteria.
The Baseline/Screening version of the scale combines the Baseline and Screening forms to assess suicidality in a patient’s lifetime and during a predefined time period. This version can assess a patient’s lifetime suicidality for data collection purposes as well as eligibility based on inclusion/exclusion criteria.
Scoring and Data Analysis Guide_Cross-Industry Working Group